A matter of concern – Trace element dyshomeostasis and genomic stability in neurons

A matter of concern – Trace element dyshomeostasis and genomic stability in neurons

Neurons are post-mitotic cells in the brain and their integrity is of central importance to avoid neurodegeneration. Yet, the inability of self-replenishment of post-mitotic cells results in the need to withstand challenges from numerous stressors during life. Neurons are exposed to oxidative stress...

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Bibliographic Details
Main Authors: Viktoria K. Wandt, Nicola Winkelbeiner, Julia Bornhorst, Barbara Witt, Stefanie Raschke, Luise Simon, Franziska Ebert, Anna P. Kipp, Tanja Schwerdtle
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Redox Biology
Subjects:
Trace elements
Trace element homeostasis
Brain
DNA damage (response)
Base excision repair
Genome stability
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231721000252

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http://www.sciencedirect.com/science/article/pii/S2213231721000252

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