T Cell Receptor Beta-Chain Profiling of Tumor Tissue, Peripheral Blood and Regional Lymph Nodes From Patients With Papillary Thyroid Carcinoma

T Cell Receptor Beta-Chain Profiling of Tumor Tissue, Peripheral Blood and Regional Lymph Nodes From Patients With Papillary Thyroid Carcinoma

Objective: To study the characteristics of the T cell receptor (TCR) repertoire in cancer tissue, peripheral blood and regional lymph nodes (LNs) from patients with papillary thyroid carcinoma (PTC).Methods: PTC tissue, peripheral blood mononuclear cells (PBMCs) and regional LNs of six patients with...

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Bibliographic Details
Main Authors: Yizeng Wang, Yuanchao Liu, Li Chen, Zuoyu Chen, Xiaoning Wang, Ruoyu Jiang, Ke Zhao, Xianghui He
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
papillary thyroid carcinoma
high-throughput sequencing
TCR repertoire
T cell receptor
high expansion clones
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.595355/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.595355/full

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