The lhfpl5 Ohnologs lhfpl5a and lhfpl5b Are Required for Mechanotransduction in Distinct Populations of Sensory Hair Cells in Zebrafish

The lhfpl5 Ohnologs lhfpl5a and lhfpl5b Are Required for Mechanotransduction in Distinct Populations of Sensory Hair Cells in Zebrafish

Hair cells sense and transmit auditory, vestibular, and hydrodynamic information by converting mechanical stimuli into electrical signals. This process of mechano-electrical transduction (MET) requires a mechanically gated channel localized in the apical stereocilia of hair cells. In mice, lipoma HM...

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Bibliographic Details
Main Authors: Timothy Erickson, Itallia V. Pacentine, Alexandra Venuto, Rachel Clemens, Teresa Nicolson
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
hair cell
mechanotransduction
deafness
lateral line
zebrafish
LHFPL5
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00320/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2019.00320/full

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