Conformational reorganization of the SARS coronavirus spike following receptor binding: implications for membrane fusion.

The SARS coronavirus (SARS-CoV) spike is the largest known viral spike molecule, and shares a similar function with all class 1 viral fusion proteins. Previous structural studies of membrane fusion proteins have largely used crystallography of static molecular fragments, in isolation of their transm...

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Bibliographic Details
Main Authors: Daniel R Beniac, Shauna L deVarennes, Anton Andonov, Runtao He, Tim F Booth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2034598?pdf=render