Small RNA sequencing-microarray analyses in Parkinson leukocytes reveal deep brain stimulation-induced and splicing changes that classify brain region transcriptomes

Small RNA sequencing-microarray analyses in Parkinson leukocytes reveal deep brain stimulation-induced and splicing changes that classify brain region transcriptomes

MicroRNAs (miRNAs) are key post transcriptional regulators of their multiple target genes. However, the detailed profile of miRNA expression in Parkinson's disease, the second most common neurodegenerative disease worldwide and the first motor disorder has not been charted yet. Here, we report...

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Bibliographic Details
Main Authors: Lilach eSoreq, Nathan eSalomonis, Michal eBronstein, David S. Greenberg, Zvi eIsrael, Hagai eBergman, Hermona eSoreq
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-05-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Blood
Brain
Deep Brain Stimulation
Leukocytes
Substantia Nigra
Parkinson’s disease
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2013.00010/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnmol.2013.00010/full

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