Carbazole Derivatives’ Binding to c-KIT G-Quadruplex DNA

The binding affinities of three carbazole derivatives to the intramolecular G-quadruplex (GQ) DNA formed by the sequence 5′-AGGGAGGGCGCTGGGAGGAGGG-3′, derived from the c-KIT 1 oncogene region, were investigated. All carbazole cationic ligands that differed in the substituents on...

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Bibliographic Details
Main Authors: Agata Głuszyńska, Bernard Juskowiak, Martyna Kuta-Siejkowska, Marcin Hoffmann, Shozeb Haider
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/23/5/1134