Dietary protein restriction increases hepatic leptin receptor mRNA and plasma soluble leptin receptor in male rodents.

Leptin is an adipokine that regulates adipose tissue mass through membrane-anchored leptin receptor (Ob-R). Extracellular domain of Ob-R in plasma is called soluble leptin receptor (sOb-R), and is the main leptin-binding protein. Based on a previous DNA microarray analysis that showed induction of h...

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Bibliographic Details
Main Authors: Riho Yamada, Shizuka Odamaki, Masaya Araki, Tasuku Watanabe, Keigo Matsuo, Kaito Uchida, Taku Kato, Yori Ozaki-Masuzawa, Asako Takenaka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0219603