Improved Immune Responses in Young and Aged Mice with Adjuvanted Vaccines against H1N1 Influenza Infection

Improved Immune Responses in Young and Aged Mice with Adjuvanted Vaccines against H1N1 Influenza Infection

Elderly people are at high risk for influenza-related morbidity and mortality due to progressive immunosenescence. While toll-like receptor (TLR) agonist containing adjuvants, and other adjuvants, have been shown to enhance influenza vaccine-induced protective responses, the mechanisms underlying ho...

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Bibliographic Details
Main Authors: Susan L. Baldwin, Fan-Chi Hsu, Neal Van Hoeven, Emily Gage, Brian Granger, Jeffrey A. Guderian, Sasha E. Larsen, Erica C. Lorenzo, Laura Haynes, Steven G. Reed, Rhea N. Coler
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Immunology
Subjects:
influenza
vaccine
adjuvant
elderly
T helper 1
H1N1
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00295/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00295/full

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