Mutual Expression of ALDH1A1, LOX, and Collagens in Ovarian Cancer Cell Lines as Combined CSCs- and ECM-Related Models of Drug Resistance Development

Mutual Expression of ALDH1A1, LOX, and Collagens in Ovarian Cancer Cell Lines as Combined CSCs- and ECM-Related Models of Drug Resistance Development

A major contributor leading to treatment failure of ovarian cancer patients is the drug resistance of cancer cell. CSCs- (cancer stem cells) and ECM (extracellular matrix)-related models of drug resistance are described as independently occurring in cancer cells. Lysyl oxidase (LOX) is another extra...

Full description

Bibliographic Details
Main Authors: Karolina Sterzyńska, Andrzej Klejewski, Karolina Wojtowicz, Monika Świerczewska, Marta Nowacka, Dominika Kaźmierczak, Małgorzata Andrzejewska, Damian Rusek, Maciej Brązert, Jacek Brązert, Michał Nowicki, Radosław Januchowski
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:International Journal of Molecular Sciences
Subjects:
lysyl oxidase (LOX)
aldehyde dehydrogenase (ALDH1A1)
collagen
cancer stem cells (CSCs)
extracellular matrix (ECM)
ovarian cancer
Online Access:http://www.mdpi.com/1422-0067/20/1/54

Internet

http://www.mdpi.com/1422-0067/20/1/54

Similar Items