Nano and Microparticulate Chitosan Based System for Formulation of Carvedilol Rapid Melt Tablet
Purpose: In the present study rapid melt tablets (RMT’s) of carvedilol were prepared by using ionotropic-gelated chitosan nanoparticles using a spray-drying method. Carvedilol is beta-adrenergic antagonist and its oral bioavailability is about 25-35% because of first pass metabolism. Methods: Th...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Tabriz University of Medical Sciences
2015-06-01
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Series: | Advanced Pharmaceutical Bulletin |
Subjects: | |
Online Access: | http://journals.tbzmed.ac.ir/APB/Abstract/APB_808_20130724143728 |