Nano and Microparticulate Chitosan Based System for Formulation of Carvedilol Rapid Melt Tablet

Purpose: In the present study rapid melt tablets (RMT’s) of carvedilol were prepared by using ionotropic-gelated chitosan nanoparticles using a spray-drying method. Carvedilol is beta-adrenergic antagonist and its oral bioavailability is about 25-35% because of first pass metabolism. Methods: Th...

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Bibliographic Details
Main Authors: Ravindra Patil, Vishal Pande, Raju Sonawane
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2015-06-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Online Access:http://journals.tbzmed.ac.ir/APB/Abstract/APB_808_20130724143728