Mitochondrial MPTP: A Novel Target of Ethnomedicine for Stroke Treatment by Apoptosis Inhibition

Mammalian mitochondrial permeability transition pore (MPTP), across the inner and outer membranes of mitochondria, is a nonspecific channel for signal transduction or material transfer between mitochondrial matrix and cytoplasm such as maintenance of Ca2+ homeostasis, regulation of oxidative stress...

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Bibliographic Details
Main Authors: Yangxin Li, Jiayi Sun, Ruixia Wu, Jinrong Bai, Ya Hou, Yong Zeng, Yi Zhang, Xiaobo Wang, Zhang Wang, Xianli Meng
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00352/full