Poly(ADP-ribosylation) is present in murine sciatic nerve fibers and is altered in a Charcot-Marie-Tooth-1E neurodegenerative model

Poly(ADP-ribosylation) is present in murine sciatic nerve fibers and is altered in a Charcot-Marie-Tooth-1E neurodegenerative model

Background Poly-ADP-ribose (PAR) is a polymer synthesized by poly-ADP-ribose polymerases (PARPs) as a postranslational protein modification and catabolized mainly by poly-ADP-ribose glycohydrolase (PARG). In spite of the existence of cytoplasmic PARPs and PARG, research has been focused on nuclear P...

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Bibliographic Details
Main Authors: Laura I. Lafon Hughes, Carlos J. Romeo Cardeillac, Karina B. Cal Castillo, Salomé C. Vilchez Larrea, José R. Sotelo Sosa, Gustavo A. Folle Ungo, Silvia H. Fernández Villamil, Alejandra E. Kun González
Format: Article
Language:English
Published: PeerJ Inc. 2017-05-01
Series:PeerJ
Subjects:
Poly(ADP-ribosylation)
Sciatic nerve
Trembler-J
Actin cytoskeleton
CMT-1E
Adherens junctions
Online Access:https://peerj.com/articles/3318.pdf

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https://peerj.com/articles/3318.pdf

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