Downregulation of Fat Mass and Obesity Associated (FTO) Promotes the Progression of Intrahepatic Cholangiocarcinoma

Intrahepatic cholangiocarcinoma (ICC) ranks as the second most malignant type of primary liver cancer with a high degree of incidence and a very poor prognosis. Fat mass and obesity-associated protein (FTO) functions as an eraser of the RNA m6A modification, but its roles in ICC tumorigenesis and de...

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Bibliographic Details
Main Authors: Zhuo-Xian Rong, Zhi Li, Jun-Ju He, Li-Yu Liu, Xin-Xin Ren, Jie Gao, Yun Mu, Yi-Di Guan, Yu-Mei Duan, Xiu-Ping Zhang, De-Xiang Zhang, Nan Li, Yue-Zhen Deng, Lun-Quan Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Oncology
Subjects:
FTO
ICC
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00369/full