Polycomb Repressor Complex 1 Member, BMI1 Contributes to Urothelial Tumorigenesis through p16-Independent Mechanisms

Urothelial carcinoma (UC) causes significant morbidity and remains the most expensive cancer to treat because of the need for repeated resections and lifelong monitoring for patients with non–muscle-invasive bladder cancer (NMIBC). Novel therapeutics and stratification approaches are needed to impro...

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Bibliographic Details
Main Authors: Lia E. De Faveri, Carolyn D. Hurst, Jo-An Roulson, Henry Wood, Marta Sanchez-Carbayo, Margaret A. Knowles, Emma J. Chapman
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523315000698