Cilia, ciliopathies and hedgehog-related forebrain developmental disorders
Development of the forebrain critically depends on the Sonic Hedgehog (Shh) signaling pathway, as illustrated in humans by the frequent perturbation of this pathway in holoprosencephaly, a condition defined as a defect in the formation of midline structures of the forebrain and face. The Shh pathway...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-03-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S096999612030512X |