Generation and characterisation of novel pancreatic adenocarcinoma xenograft models and corresponding primary cell lines.

Pancreatic adenocarcinoma is one of the most lethal cancer types, currently lacking efficient treatment. The heterogeneous nature of these tumours are poorly represented by the classical pancreatic cell lines, which have been through strong clonal selection in vitro, and are often derived from metas...

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Bibliographic Details
Main Authors: Anna B Wennerström, Inger Marie Bowitz Lothe, Vandana Sandhu, Elin H Kure, Ola Myklebost, Else Munthe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4141735?pdf=render