Increased Neurofilament Light Chain and YKL-40 CSF Levels in One Japanese IBMPFD Patient With VCP R155C Mutation: A Clinical Case Report With CSF Biomarker Analyses

Increased Neurofilament Light Chain and YKL-40 CSF Levels in One Japanese IBMPFD Patient With VCP R155C Mutation: A Clinical Case Report With CSF Biomarker Analyses

Inclusion body myopathy (IBM) with Paget's disease of bone (PDB) and frontotemporal dementia (IBMPFD) presents with multiple symptoms and an unknown etiology. Valosin-containing protein (VCP) has been identified as the main causative gene of IBMPFD. However, no studies on neurofilament light ch...

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Bibliographic Details
Main Authors: Masaki Ikeda, Takeo Kuwabara, Eriko Takai, Hiroo Kasahara, Minori Furuta, Akiko Sekine, Kouki Makioka, Tsuneo Yamazaki, Yukio Fujita, Kazuaki Nagashima, Tetsuya Higuchi, Yoshito Tsushima, Yoshio Ikeda
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Neurology
Subjects:
IBMPFD
VCP
mutation
CSF
NFL
YKL-40
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00757/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2020.00757/full

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