Severe hypoxia induces chemo-resistance in clinical cervical tumors through MVP over-expression

Severe hypoxia induces chemo-resistance in clinical cervical tumors through MVP over-expression

<p>Abstract</p> <p>Oxygen molecule modulates tumour response to radiotherapy. Higher radiation doses are required under hypoxic conditions to induce cell death. Hypoxia may inhibit the non-homologous end-joining DNA repair through down regulating Ku70/80 expression. Hypoxia induces...

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Bibliographic Details
Main Authors: Apolinario Rosa M, Clavo Bernardino, Lloret Marta, Lara Pedro C, Henríquez-Hernández Luis, Bordón Elisa, Fontes Fausto, Rey Agustín
Format: Article
Language:English
Published: BMC 2009-08-01
Series:Radiation Oncology
Online Access:http://www.ro-journal.com/content/4/1/29

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http://www.ro-journal.com/content/4/1/29

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