Synthesis of a novel PEGylated colon-specific azo-based 4- aminosalicylic acid prodrug

<em><strong>Objective(s):</strong></em> 4-aminosalicylic acid (4-ASA) is an isomer of mesalazine that has recently been shown to be effective against inflammatory bowel disease (IBD), and more specifically, ulcerative colitis. However, the majority of orally administered 4-AS...

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Bibliographic Details
Main Authors: Fatemeh Sadeghi, Atie Eidizade, Farinaz Saremnejad, Farzin Hadizadeh, Elham Khodaverdi, Abbas Akhgari
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2020-06-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
ibd
Online Access:http://ijbms.mums.ac.ir/article_15505_e48256dd8798fffbcd0c469a04d4ac20.pdf