Reproducible In Vitro Tissue Culture Model to Study Basic Mechanisms of Calcific Aortic Valve Disease: Comparative Analysis to Valvular Interstitials Cells

Reproducible In Vitro Tissue Culture Model to Study Basic Mechanisms of Calcific Aortic Valve Disease: Comparative Analysis to Valvular Interstitials Cells

The hallmarks of calcific aortic valve disease (CAVD), an active and regulated process involving the creation of calcium nodules, lipoprotein accumulation, and chronic inflammation, are the significant changes that occur in the composition, organization, and mechanical properties of the extracellula...

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Bibliographic Details
Main Authors: Andreas Weber, Melissa Pfaff, Friederike Schöttler, Vera Schmidt, Artur Lichtenberg, Payam Akhyari
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Biomedicines
Subjects:
aortic valve stenosis
calcific aortic valve disease
CAVD
calcification
degeneration
Online Access:https://www.mdpi.com/2227-9059/9/5/474

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https://www.mdpi.com/2227-9059/9/5/474

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