Reproducible In Vitro Tissue Culture Model to Study Basic Mechanisms of Calcific Aortic Valve Disease: Comparative Analysis to Valvular Interstitials Cells
The hallmarks of calcific aortic valve disease (CAVD), an active and regulated process involving the creation of calcium nodules, lipoprotein accumulation, and chronic inflammation, are the significant changes that occur in the composition, organization, and mechanical properties of the extracellula...
Main Authors: | Andreas Weber, Melissa Pfaff, Friederike Schöttler, Vera Schmidt, Artur Lichtenberg, Payam Akhyari |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-04-01
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Series: | Biomedicines |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9059/9/5/474 |
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