Randomized feasibility trial to assess tolerance and clinical effects of lithium in progressive multiple sclerosis

Background: Disability accumulation in progressive multiple sclerosis (MS) results from inflammatory and neurodegenerative mechanisms. In animal models of MS, lithium acts to reduce inflammatory demyelination, and in models of neurodegenerative diseases, lithium also slows neuronal death. Prospectiv...

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Bibliographic Details
Main Authors: John R. Rinker, II, William R. Meador, Peter King
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020313724