Potent and specific antitumor effect for colorectal cancer by CEA and Rb double regulated oncolytic adenovirus harboring ST13 gene.

Potent and specific antitumor effect for colorectal cancer by CEA and Rb double regulated oncolytic adenovirus harboring ST13 gene.

Cancer Targeting Gene-Viro-Therapy (CTGVT) is constructed by inserting an antitumor gene into an oncolytic virus (OV). It is actually an OV-gene therapy, which has much better antitumor effect than either gene therapy alone or virotherapy alone in our previously published papers. This study is a mod...

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Bibliographic Details
Main Authors: Xiumei Zhou, Guoliang Xie, Shibing Wang, Yigang Wang, Kangjian Zhang, Shu Zheng, Liang Chu, Lianli Xiao, Yuemei Yu, Yue Zhang, Xinyuan Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3471845?pdf=render

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http://europepmc.org/articles/PMC3471845?pdf=render

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