Phosphatase and tensin homolog deleted on chromosome 10 degradation induced by NEDD4 promotes acquired erlotinib resistance in non–small-cell lung cancer
Acquired resistance to epidermal growth factor receptor-tyrosine kinase inhibitors, such as gefitinib and erlotinib, is a critical issue in the treatment of patients with epidermal growth factor receptor mutant–positive non–small-cell lung cancer. Recent evidence suggests that downregulation of gene...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
IOS Press
2017-07-01
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Series: | Tumor Biology |
Online Access: | https://doi.org/10.1177/1010428317709639 |