Therapeutic Targeting of Transcription Factors to Control the Cytokine Release Syndrome in COVID-19

Therapeutic Targeting of Transcription Factors to Control the Cytokine Release Syndrome in COVID-19

Treatment of the cytokine release syndrome (CRS) has become an important part of rescuing hospitalized COVID-19 patients. Here, we systematically explored the transcriptional regulators of inflammatory cytokines involved in the COVID-19 CRS to identify candidate transcription factors (TFs) for thera...

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Bibliographic Details
Main Authors: Clarissa S. Santoso, Zhaorong Li, Jaice T. Rottenberg, Xing Liu, Vivian X. Shen, Juan I. Fuxman Bass
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Pharmacology
Subjects:
COVID-19
cytokine release syndrome
cytokine storm
drug repurposing
transcriptional regulators
SARS-CoV2
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.673485/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.673485/full

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