Immunochemical Approach for Monitoring of Structural Transition of ApoA-I upon HDL Formation Using Novel Monoclonal Antibodies

Immunochemical Approach for Monitoring of Structural Transition of ApoA-I upon HDL Formation Using Novel Monoclonal Antibodies

Abstract Apolipoprotein A-I (apoA-I) undergoes a large conformational reorganization during remodeling of high-density lipoprotein (HDL) particles. To detect structural transition of apoA-I upon HDL formation, we developed novel monoclonal antibodies (mAbs). Splenocytes from BALB/c mice immunized wi...

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Bibliographic Details
Main Authors: Hitoshi Kimura, Shiho Mikawa, Chiharu Mizuguchi, Yuki Horie, Izumi Morita, Hiroyuki Oyama, Takashi Ohgita, Kazuchika Nishitsuji, Atsuko Takeuchi, Sissel Lund-Katz, Kenichi Akaji, Norihiro Kobayashi, Hiroyuki Saito
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-03208-8

Internet

https://doi.org/10.1038/s41598-017-03208-8

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