Antioxidant and Anti-Inflammatory Strategies Based on the Potentiation of Glutathione Peroxidase Activity Prevent Endothelial Dysfunction in Chronic Kidney Disease

Antioxidant and Anti-Inflammatory Strategies Based on the Potentiation of Glutathione Peroxidase Activity Prevent Endothelial Dysfunction in Chronic Kidney Disease

Background/Aims: Accelerated atherosclerosis in chronic kidney disease (CKD) is preceded by endothelial dysfunction (ED), which exhibits a proinflammatory and prothrombotic phenotype and enhanced oxidative stress. In this study, the effect of several compounds with anti-inflammatory and/or antioxida...

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Bibliographic Details
Main Authors: Manel Vera, Sergi Torramade-Moix, Susana Martin-Rodriguez, Aleix Cases, Josep M. Cruzado, Jose Rivera, Gines Escolar, Marta Palomo, Maribel Diaz-Ricart
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Endothelial dysfunction
Uremia
Antioxidants
Flavonoids
Glutathione peroxidase
Ebselen
N-acetylcysteine
Online Access:https://www.karger.com/Article/FullText/495540

Internet

https://www.karger.com/Article/FullText/495540

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