Neonatal hypoxic preconditioning involves vascular endothelial growth factor

We studied hypoxic preconditioning (HxP) in the murine developing brain, focusing on the role for vascular endothelial growth factor (VEGF). Newborn mice were used as follows: (1) HxP (or normoxia) then intracerebral (i.c.) NMDA or AMPA-kainate agonist; (2) HxP then intraperitoneal (i.p.) anti-VEGFR...

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Bibliographic Details
Main Authors: Vincent Laudenbach, Romain H. Fontaine, Fadia Medja, Peter Carmeliet, Daniel J. Hicklin, Jorge Gallego, Philippe Leroux, Stéphane Marret, Pierre Gressens
Format: Article
Language:English
Published: Elsevier 2007-04-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996107000022