Differential Regulation of LPS-Mediated VE-Cadherin Disruption in Human Endothelial Cells and the Underlying Signaling Pathways: A Mini Review

Differential Regulation of LPS-Mediated VE-Cadherin Disruption in Human Endothelial Cells and the Underlying Signaling Pathways: A Mini Review

Endothelial cells lining the inner vascular wall form a monolayer that contributes to the selective permeability of endothelial barrier. This selective permeability is mainly regulated by an endothelium-specific adherens junctional protein, known as vascular endothelial-cadherin (VE-cadherin). In en...

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Bibliographic Details
Main Authors: Yee Han Chan, Hanis Hazeera Harith, Daud Ahmad Israf, Chau Ling Tham
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
VE-cadherin
adherens junction
lipopolysaccharide
endothelial hyperpermeability
tyrosine phosphorylation
internalization
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00280/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2019.00280/full

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