Topical steroid versus placebo for the prevention of radiation dermatitis in head and neck cancer patients receiving chemoradiotherapy: the study protocol of J-SUPPORT 1602 (TOPICS study), a randomized double-blinded phase 3 trial

Topical steroid versus placebo for the prevention of radiation dermatitis in head and neck cancer patients receiving chemoradiotherapy: the study protocol of J-SUPPORT 1602 (TOPICS study), a randomized double-blinded phase 3 trial

Abstract Background To date, the clinical benefit of topical steroid use has only been demonstrated for radiation dermatitis induced by 50–60 Gy irradiation in breast cancer. However, these agents are also often used clinically for the control of radiation dermatitis induced by high-dose (>60Gy)...

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Bibliographic Details
Main Authors: Sadamoto Zenda, Takuhiro Yamaguchi, Tomoya Yokota, Tempei Miyaji, Tomoe Mashiko, Mari Tanaka, Masahito Yonemura, Misaki Takeno, Tomoka Okano, Toshikatsu Kawasaki, Yuko Nakamori, Shinobu Ishii, Sanae Shimada, Miyuki Kanamaru, Yosuke Uchitomi
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Cancer
Subjects:
Head and neck
Chemoradiotherapy
Radiation dermatitis
Nursing
Topical steroid
Online Access:http://link.springer.com/article/10.1186/s12885-018-4763-1

Internet

http://link.springer.com/article/10.1186/s12885-018-4763-1

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