Soluble TNF mediates the transition from pulmonary inflammation to fibrosis.

BACKGROUND: Fibrosis, the replacement of functional tissue with excessive fibrous tissue, can occur in all the main tissues and organ systems, resulting in various pathological disorders. Idiopathic Pulmonary Fibrosis is a prototype fibrotic disease involving abnormal wound healing in response to mu...

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Bibliographic Details
Main Authors: Nikos Oikonomou, Vaggelis Harokopos, Jonathan Zalevsky, Christos Valavanis, Anastasia Kotanidou, David E Szymkowski, George Kollias, Vassilis Aidinis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1762410?pdf=render