The DNA methylome of glioblastoma multiforme

Glioblastoma multiforme (GBM) is the most frequent brain tumor in adults. This lethal cancer is a challenge in neuro-oncology since patients almost invariably succumb to the disease. Intensive molecular studies have revealed a variety of deregulated genetic pathways involved in DNA repair, apoptosis...

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Bibliographic Details
Main Authors: Ramon Martinez, Manel Esteller
Format: Article
Language:English
Published: Elsevier 2010-07-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996110000021