Improving the efficacy of osteosarcoma therapy: combining drugs that turn cancer cell ‘don't eat me’ signals off and ‘eat me’ signals on

Improving the efficacy of osteosarcoma therapy: combining drugs that turn cancer cell ‘don't eat me’ signals off and ‘eat me’ signals on

The long‐term survival of osteosarcoma patients with metastatic or recurrent disease remains dismal, and new therapeutic options are urgently needed. The purpose of our study was to compare the efficacy of CD47 mAb plus doxorubicin combination therapy in mouse models of osteosarcoma with CD47 mAb an...

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Bibliographic Details
Main Authors: Suchismita Mohanty, Maryam Aghighi, Ketan Yerneni, Johanna Lena Theruvath, Heike E. Daldrup‐Link
Format: Article
Language:English
Published: Wiley 2019-10-01
Series:Molecular Oncology
Subjects:
bone sarcoma
CD47
doxorubicin
ferumoxytol
macrophages
MR imaging
Online Access:https://doi.org/10.1002/1878-0261.12556

Internet

https://doi.org/10.1002/1878-0261.12556

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