Role of rhesus macaque IFITM3(2) in simian immunodeficiency virus infection of macaques.

The experimental infection of rhesus macaques (rh) with simian immunodeficiency virus (SIV) is an important model for human immunodeficiency virus (HIV) infection of humans. The interferon-induced transmembrane protein 3 (IFITM3) inhibits HIV and SIV infection at the stage of host cell entry. Howeve...

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Bibliographic Details
Main Authors: Michael Winkler, Sabine Gärtner, Lara Markus, Markus Hoffmann, Inga Nehlmeier, Michael Krawczak, Ulrike Sauermann, Stefan Pöhlmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0224082