Optimized production of a biologically active Clostridium perfringens glycosyl hydrolase phage endolysin PlyCP41 in plants using virus-based systemic expression

Optimized production of a biologically active Clostridium perfringens glycosyl hydrolase phage endolysin PlyCP41 in plants using virus-based systemic expression

Abstract Background Clostridium perfringens, a gram-positive, anaerobic, rod-shaped bacterium, is the third leading cause of human foodborne bacterial disease and a cause of necrotic enteritis in poultry. It is controlled using antibiotics, widespread use of which may lead to development of drug-res...

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Bibliographic Details
Main Authors: Rosemarie W. Hammond, Steven M. Swift, Juli A. Foster-Frey, Natalia Y. Kovalskaya, David M. Donovan
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Biotechnology
Subjects:
Alternative antimicrobial
Bacteriophage
Endolysin
Nicotiana benthamiana
Plant production of recombinant proteins
Plant virus-based gene expression
Online Access:https://doi.org/10.1186/s12896-019-0594-7

Internet

https://doi.org/10.1186/s12896-019-0594-7

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