Antibody landscape against SARS-CoV-2 reveals significant differences between non-structural/accessory and structural proteins

Antibody landscape against SARS-CoV-2 reveals significant differences between non-structural/accessory and structural proteins

Summary: The immunogenicity of the SARS-CoV-2 proteome is largely unknown, especially for non-structural proteins and accessory proteins. In this study, we collect 2,360 COVID-19 sera and 601 control sera. We analyze these sera on a protein microarray with 20 proteins of SARS-CoV-2, building an anti...

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Bibliographic Details
Main Authors: Yang Li, Zhaowei Xu, Qing Lei, Dan-yun Lai, Hongyan Hou, He-wei Jiang, Yun-xiao Zheng, Xue-ning Wang, Jiaoxiang Wu, Ming-liang Ma, Bo Zhang, Hong Chen, Caizheng Yu, Jun-biao Xue, Hai-nan Zhang, Huan Qi, Shu-juan Guo, Yandi Zhang, Xiaosong Lin, Zongjie Yao, Huiming Sheng, Ziyong Sun, Feng Wang, Xionglin Fan, Sheng-ce Tao
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Cell Reports
Subjects:
humoral immunity
non-structural/accessory proteins
SARS-CoV-2
COVID-19
proteome microarray
immune response
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721007890

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http://www.sciencedirect.com/science/article/pii/S2211124721007890

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