Transcriptional profiles of valvular interstitial cells cultured on tissue culture polystyrene, on 2D hydrogels, or within 3D hydrogels

Valvular interstitial cells (VICs) actively maintain and repair heart valve tissue; however, persistent activation of VICs to a myofibroblast phenotype can lead to aortic stenosis (Chen and Simmons, 2011) [1]. To better understand and quantify how microenvironmental cues influence VIC phenotype, we...

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Bibliographic Details
Main Authors: Kelly M. Mabry, Samuel Z. Payne, Kristi S. Anseth
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:Data in Brief
Online Access:http://www.sciencedirect.com/science/article/pii/S2352340915003121