Fexofenadine Protects Against Intervertebral Disc Degeneration Through TNF Signaling

Fexofenadine Protects Against Intervertebral Disc Degeneration Through TNF Signaling

Objective: Fexofenadine (FFD) is an antihistamine drug with an anti-inflammatory effect. The intervertebral disc (IVD) degeneration process is involved in inflammation in which tumor necrosis factor-α (TNF-α) plays an important role. This study aims to investigate the role of FFD in the pathological...

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Bibliographic Details
Main Authors: Kaiwen Liu, Jianlu Wei, Guohua Li, Ronghan Liu, Dawang Zhao, Yuanqiang Zhang, Jie Shi, Qing Xie, Lei Cheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
intervertebral disc degeneration
fexofenadine
TNF-α
inflammation
CPLA2
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.687024/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.687024/full

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