Efficiency of dendritic cell vaccination against B16 melanoma depends on the immunization route.

Dendritic cells (DC) presenting tumor antigens are crucial to induce potent T cell-mediated anti-tumor immune responses. Therefore DC-based cancer vaccines have been established for therapy, however clinical outcomes are often poor and need improvement. Using a mouse model of B16 melanoma, we found...

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Bibliographic Details
Main Authors: Fanny Edele, Jan C Dudda, Eva Bachtanian, Thilo Jakob, Hanspeter Pircher, Stefan F Martin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4133283?pdf=render