Human Mesenchymal Stromal Cell (MSC) Characteristics Vary Among Laboratories When Manufactured From the Same Source Material: A Report by the Cellular Therapy Team of the Biomedical Excellence for Safer Transfusion (BEST) Collaborative

Human Mesenchymal Stromal Cell (MSC) Characteristics Vary Among Laboratories When Manufactured From the Same Source Material: A Report by the Cellular Therapy Team of the Biomedical Excellence for Safer Transfusion (BEST) Collaborative

BackgroundCulture-derived mesenchymal stromal cells (MSCs) exhibit variable characteristics when manufactured using different methods and different source materials. The purpose of this study was to assess the impact on MSC characteristics when different laboratories propagated MSCs from cultures in...

Full description

Bibliographic Details
Main Authors: David F. Stroncek, Ping Jin, David H. McKenna, Minoko Takanashi, Magali J. Fontaine, Shibani Pati, Richard Schäfer, Emily Peterson, Eric Benedetti, Jo-Anna Reems
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
mesenchymal stromal cells
bone marrow
variability
quality
transcriptome
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00458/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.00458/full

Similar Items