Comparative Effect of Oncolytic Adenoviruses with E1 A or E113-55 kDa Deletions in Malignant Gliomas

Comparative Effect of Oncolytic Adenoviruses with E1 A or E113-55 kDa Deletions in Malignant Gliomas

Replication-competent oncolytic adenoviruses hold considerable promise for treating malignant gliomas. The toxicity of the clinically tested Ell B-55 kDa mutant virus is negligible; however, its full clinical potential is still being evaluated. The purpose of the present study is to compare the ant...

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Bibliographic Details
Main Authors: Hong Jiang, Candelaria Gomez-Manzano, Ramon Alemany, Diana Medrano, Marta Alonso, B. Nebiyou Bekele, E Lin, Charles C. Conrad, W.K. Alfred Yung, Juan Fueyo
Format: Article
Language:English
Published: Elsevier 2005-01-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Glioma
oncolytic adenovirus
E1 A
E1 B
fiber protein
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558605800983

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http://www.sciencedirect.com/science/article/pii/S1476558605800983

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