Cаlіx[4]аrene С-956 is effective inhibitor of Н(+)-Сa(2+)-exchanger in smooth muscle mitochondria

Cаlіx[4]аrene С-956 is effective inhibitor of Н(+)-Сa(2+)-exchanger in smooth muscle mitochondria

It was shown that calix[4]arene C-956 exhibited a pronounced concentration-dependent (10-100 μM) inhibitory effect on the H+-Ca2+-exchanger of the inner mitochondrial membrane of rat uterine myocytes (Ki 35.1 ± 7.9 μM). The inhibitory effect of calix[4]arene C-956 was accompanied by a decrease in th...

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Bibliographic Details
Main Authors: G. V. Danylovych, О. V. Kоlomiets, Yu. V. Danylovych, R. V. Rodik, V. I. Kаlchenko, S. О. Kоsterin
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine and Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine. 2018-02-01
Series:Ukrainian Biochemical Journal
Subjects:
calix[4]arenes
H(+)-Ca(2+)-exchanger
mitochondria
smooth muscle
uterus
Online Access:http://ukrbiochemjournal.org/2018/02/c%d0%b0l%d1%96x4%d0%b0rene-%d1%81-956-is-effective-inhibitor-of-%d0%bd-%d1%81a2-exchanger-in-smooth-muscle-mitochondria.html

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http://ukrbiochemjournal.org/2018/02/c%d0%b0l%d1%96x4%d0%b0rene-%d1%81-956-is-effective-inhibitor-of-%d0%bd-%d1%81a2-exchanger-in-smooth-muscle-mitochondria.html

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