Exploiting Base Excision Repair to Improve Therapeutic Approaches for Pancreatic Cancer

Exploiting Base Excision Repair to Improve Therapeutic Approaches for Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDA) is a highly chemoresistant and metastatic disease with a dismal 5-year survival rate of 6%. More effective therapeutic targets and approaches are urgently needed to tackle this devastating disease. The base excision repair pathway has been identified as a predi...

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Bibliographic Details
Main Authors: George eSharbeen, Joshua eMcCarroll, David eGoldstein, Phoebe ePhillips
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Nutrition
Subjects:
Pancreatic Cancer
chemoresistance
Base excision repair
prognostic factors
therapeutic targets
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnut.2015.00010/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnut.2015.00010/full

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