The microRNA-195 - BDNF pathway and cognitive deficits in schizophrenia patients with minimal antipsychotic medication exposure

Abstract Cognitive impairment is a core characteristic of schizophrenia, but its underlying neural mechanisms remain poorly understood. Reduced brain-derived neurotrophic factor (BDNF), a protein critical for neural plasticity and synaptic signaling, is one of the few molecules consistently associat...

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Bibliographic Details
Main Authors: Shujuan Pan, Wei Feng, Yanli Li, Junchao Huang, Song Chen, Yimin Cui, Baopeng Tian, Shuping Tan, Zhiren Wang, Shangwu Yao, Joshua Chiappelli, Peter Kochunov, Shuo Chen, Fude Yang, Chiang-Shan R. Li, Li Tian, Yunlong Tan, L. Elliot Hong
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01240-x