Pharmacologic inhibition of mTORC1 mimics dietary protein restriction in a mouse model of lactation

Pharmacologic inhibition of mTORC1 mimics dietary protein restriction in a mouse model of lactation

Abstract Background Understanding the mechanisms of N utilization for lactation can lead to improved requirement estimates and increased efficiency, which modern dairy diets currently fail to maximize. The mechanistic target of rapamycin complex 1 (mTORC1) is a central hub of translation regulation,...

Full description

Bibliographic Details
Main Authors: Virginia L. Pszczolkowski, Steven J. Halderson, Emma J. Meyer, Amy Lin, Sebastian I. Arriola Apelo
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Journal of Animal Science and Biotechnology
Subjects:
Amino acids
Lactation
Mammary
Mouse model
mTORC1
Rapamycin
Online Access:http://link.springer.com/article/10.1186/s40104-020-00470-1

Internet

http://link.springer.com/article/10.1186/s40104-020-00470-1

Similar Items