Circulatory shear stress induces molecular changes and side population enrichment in primary tumor-derived lung cancer cells with higher metastatic potential

Circulatory shear stress induces molecular changes and side population enrichment in primary tumor-derived lung cancer cells with higher metastatic potential

Abstract Cancer is a leading cause of death and disease worldwide. However, while the survival for patients with primary cancers is improving, the ability to prevent metastatic cancer has not. Once patients develop metastases, their prognosis is dismal. A critical step in metastasis is the transit o...

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Bibliographic Details
Main Authors: Keila Alvarado-Estrada, Lina Marenco-Hillembrand, Sushila Maharjan, Valerio Luca Mainardi, Yu Shrike Zhang, Natanael Zarco, Paula Schiapparelli, Hugo Guerrero-Cazares, Rachel Sarabia-Estrada, Alfredo Quinones-Hinojosa, Kaisorn L. Chaichana
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-82634-1

Internet

https://doi.org/10.1038/s41598-021-82634-1

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