Differential roles of the PKC novel isoforms, PKCdelta and PKCepsilon, in mouse and human platelets.

Increasing evidence suggests that individual isoforms of protein kinase C (PKC) play distinct roles in regulating platelet activation.In this study, we focus on the role of two novel PKC isoforms, PKCdelta and PKCepsilon, in both mouse and human platelets. PKCdelta is robustly expressed in human pla...

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Bibliographic Details
Main Authors: Catherine J Pears, Kelly Thornber, Jocelyn M Auger, Craig E Hughes, Beata Grygielska, Majd B Protty, Andrew C Pearce, Steve P Watson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2583049?pdf=render