Chitosan in viscosupplementation: in vivo effect on rabbit subchondral bone

Abstract Background To investigate the effect of intra-articular injection of Chitosan (Cs) added to hyaluronic acid (HA) on subchondral bone during osteoarthritis (OA), microarchitectural parameters and mineral density were measured in a rabbit model of early OA. A novel hybrid hydrogel adding reac...

Full description

Bibliographic Details
Main Authors: R. Rieger, C. Boulocher, S. Kaderli, T. Hoc
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Musculoskeletal Disorders
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12891-017-1700-4