Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions

Ankyrins together with their spectrin partners are the master organizers of micron-scale membrane domains in diverse tissues. The 24 ankyrin (ANK) repeats of ankyrins bind to numerous membrane proteins, linking them to spectrin-based cytoskeletons at specific membrane microdomains. The accessibility...

Full description

Bibliographic Details
Main Authors: Keyu Chen, Jianchao Li, Chao Wang, Zhiyi Wei, Mingjie Zhang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-08-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/29150